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It binds to the S1P 1 receptor, which is most abundantly expressed on vascular endothelial cells, and the activation of this receptor attenuates the activity of MMPs, causing syndecan-1 ectodomain shedding (132)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.García-Niño W.R., Pedraza-Chaverrí J
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