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In addition, FLX induced apoptosis and reduced invasiveness and angiogenesis in NSCLC cells CL1-5-F4 in a dose-dependent manner both in vitro and in vivo by upregulating different caspases and suppressing VEGF, MMP-9, urokinase-uPA, and Cyclin-D1

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PLOS ONE 6 , e14664 (2011)

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