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however, when looking at the expression pattern for the enzymes tested, while taking into account how DMSO was introduced into the cells, it can be observed that the direct introduction of DMSO into the medium gives a consistent picture of the changes in the expression of the enzymes tested, regardless of whether serum was present in the medium or not (Figure 4A,B)
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The locally administered MeCbl group reported larger reductions in multiple pain measures—including continuous pain, paroxysmal pain, allodynia, and analgesic use—and also showed improvements in functional assessments
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