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Patients with controlled uric acid level and doing well on allopurinol would seem to have no reason to switch to this new agent, in view of allopurinol's lower cost and 40-year history of an overall very good safety record (see "Allopurinol" discussion above)
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In a follow-up study by the same group, intense white light exposure (400–700 nm, 5 klux, 3 h) in albino rats resulted in elevated levels of 4-HNE-protein adducts in the retina 204
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