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To determine if glutathione redox plays a role in the protective effects of ET, we used 2-Acetylamino-3-[4-(2-acetylamino-2-carboxy-ethylsulfanylthiocarbonylamino)phenylthiocarbamoylsulfanyl]propionic acid (2-AAPA) to inhibit Glutathione Reductase (Seefeldt et al., 2009, Zhao et al., 2009), an enzyme with both mitochondrial and cytosolic activities that couples NADPH oxidation to GSSG reduction
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FASEB J (2015) 29(3):796–806
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