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Analytical HPLC data indicate that Dihexa solutions begin exhibiting concentration loss and precipitation after as few as two freeze-thaw cycles
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Measuring haptoglobin levels, reticulocyte counts, elevated unconjugated bilirubin, and LDH can determine if hemolysis is present and to what degree [312], or if the anemia is primarily due to dapsone’s effect on folic acid metabolism [310]
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